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For example, K63-linked chains affect protein interactions and chromatin recruitment ( 4 E3 ligases and deubiquitinating enzymes in circadian regulation 4.1 E3 ligases and their role in circadian regulation 4.1.1 E3 ligases E3 ubiquitin ligases, though structurally built on a limited set of catalytic domains, achieve functional diversity through specialized substrate recognition and regulatory elements

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[PubMed] [Google Scholar] 86.Henry G.E., Momin R.A., Nair M.G., Dewitt D.L