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CARNITINE TRANSPORT AND FATTY ACID OXIDATION - PMC

L-carnitine deficiency severely impairs the mitochondrial import of long-chain acyl-CoAs, directly limiting the acetyl-CoA pool required for ketogenesis (3)

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Because mass and integrity of skeletal muscle are essential for whole-body metabolism and health, increasing muscle wasting is a crucial indicator that leads to treatment intolerance, a poor prognosis, and, as a result, a higher mortality rate in inpatients